In the back three, full-back Mike Haley and Darren Sweetnam make their first Guinness PRO14 appearances since February with Andrew Conway starting on the right wing.
Damian de Allende and Chris Farrell form the centre partnership with Craig Casey and JJ Hanrahan in the half-backs.
James Cronin, Rhys Marshall and John Ryan pack down in the front row with Jean Kleyn and Tadhg Beirne, who faces his former side for the first time, in the second row.
Captain Peter O’Mahony, Jack O’Donoghue and CJ Stander complete the starting XV.
Greencore Munster Rugby Academy out-half Ben Healy is among the replacements.
The Munster squad will be wearing our new adidas Alternate kit for the first time, available exclusively for pre-order at Life Style Sports Find out all you need to know ahead of the game here.
Munster: Mike Haley; Andrew Conway, Chris Farrell, Damian de Allende, Darren Sweetnam; JJ Hanrahan, Craig Casey; James Cronin, Rhys Marshall, John Ryan; Jean Kleyn, Tadhg Beirne; Peter O’Mahony (C), Jack O’Donoghue, CJ Stander.
Replacements: Kevin O’Byrne, Jeremy Loughman, Stephen Archer, Fineen Wycherley, Gavin Coombes, Neil Cronin, Ben Healy, Rory Scannell.
Munster Rugby are offering supporters the chance to have a cardboard cut-out of themselves in Thomond Park for the opening games of the Guinness PRO14 season.
The cut-outs will remain in place while the stadium capacity is limited.
Supporters can buy a single cardboard cut-out for €19.95 or three for €49.95.
See full details and order here.
Please note that if you order later than noon on Friday, October 2, your cut-out will be in place for our second home game of the season.